Carbapenemases in enterobacteria, Hong Kong, China, 2009.
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ABSTRACT:
SUBMITTER: Chu YW
PROVIDER: S-EPMC3204654 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Publications
Carbapenemases in enterobacteria, Hong Kong, China, 2009.
Chu Yiu-Wai YW Tung Viola W N VW Cheung Terence K M TK Chu Man-Yu MY Cheng Naomi N Lai Christopher C Tsang Dominic N C DN Lo Janice Y C JY
Emerging infectious diseases 20110101 1
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Project description:BackgroundAlthough deaths associated with laboratory-confirmed influenza virus infections are rare, the excess mortality burden of influenza estimated from statistical models may more reliably quantify the impact of influenza in a population.MethodsWe applied age-specific multiple linear regression models to all-cause and cause-specific mortality rates in Hong Kong from 1998 through 2009. The differences between estimated mortality rates in the presence or absence of recorded influenza activity were used to estimate influenza-associated excess mortality.ResultsThe annual influenza-associated all-cause excess mortality rate was 11.1 (95% confidence interval [CI], 7.2-14.6) per 100,000 person-years. We estimated an average of 751 (95% CI, 488-990) excess deaths associated with influenza annually from 1998 through 2009, with 95% of the excess deaths occurring in persons aged ?65 years. Most of the influenza-associated excess deaths were from respiratory (53%) and cardiovascular (18%) causes. Influenza A(H3N2) epidemics were associated with more excess deaths than influenza A(H1N1) or B during the study period.ConclusionsInfluenza was associated with a substantial number of excess deaths each year, mainly among the elderly, in Hong Kong in the past decade. The influenza-associated excess mortality rates were generally similar in Hong Kong and the United States.
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