Lipid chaperones and metabolic inflammation.
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ABSTRACT:
SUBMITTER: Furuhashi M
PROVIDER: S-EPMC3206330 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Publications
Lipid chaperones and metabolic inflammation.
Furuhashi Masato M Ishimura Shutaro S Ota Hideki H Miura Tetsuji T
International journal of inflammation 20111030
Over the past decade, a large body of evidence has emerged demonstrating an integration of metabolic and immune response pathways. It is now clear that obesity and associated disorders such as insulin resistance and type 2 diabetes are associated with a metabolically driven, low-grade, chronic inflammatory state, referred to as "metaflammation." Several inflammatory cytokines as well as lipids and metabolic stress pathways can activate metaflammation, which targets metabolically critical organs ...[more]
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