Ontology highlight
ABSTRACT:
SUBMITTER: Pepper M
PROVIDER: S-EPMC3208313 | biostudies-literature | 2011 Oct
REPOSITORIES: biostudies-literature
Immunity 20111020 4
Listeria monocytogenes infection generates T helper 1 (Th1) effector memory cells and CC chemokine receptor 7 (CCR7)(+) cells resembling central memory cells. We tracked endogenous L. monocytogenes-specific CD4(+) T cells to determine how these memory cells are formed. Two effector cell populations were already present several days after infection. One highly expressed the T-bet transcription factor and produced Th1 memory cells in an interleukin-2 (IL-2) receptor-dependent fashion. The other re ...[more]