Ontology highlight
ABSTRACT:
SUBMITTER: Park G
PROVIDER: S-EPMC3209061 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
Park Gyungsoon G Servin Jacqueline A JA Turner Gloria E GE Altamirano Lorena L Colot Hildur V HV Collopy Patrick P Litvinkova Liubov L Li Liande L Jones Carol A CA Diala Fitz-Gerald FG Dunlap Jay C JC Borkovich Katherine A KA
Eukaryotic cell 20110930 11
Serine/threonine (S/T) protein kinases are crucial components of diverse signaling pathways in eukaryotes, including the model filamentous fungus Neurospora crassa. In order to assess the importance of S/T kinases to Neurospora biology, we embarked on a global analysis of 86 S/T kinase genes in Neurospora. We were able to isolate viable mutants for 77 of the 86 kinase genes. Of these, 57% exhibited at least one growth or developmental phenotype, with a relatively large fraction (40%) possessing ...[more]