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Decay of a model mRNA in Bacillus subtilis by a combination of RNase J1 5' exonuclease and RNase Y endonuclease activities.

ABSTRACT: The involvement of the recently characterized 5' exonuclease activity of RNase J1 and endonuclease activity of RNase Y in the turnover of ?ermC mRNA in Bacillus subtilis was investigated. Evidence is presented that both of these activities determine the half-life of ?ermC mRNA.

SUBMITTER: Yao S

PROVIDER: S-EPMC3209221 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature

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Decay of a model mRNA in Bacillus subtilis by a combination of RNase J1 5' exonuclease and RNase Y endonuclease activities.

Yao Shiyi S Richards Jamie J Belasco Joel G JG Bechhofer David H DH

Journal of bacteriology 20110909 22

The involvement of the recently characterized 5' exonuclease activity of RNase J1 and endonuclease activity of RNase Y in the turnover of ΔermC mRNA in Bacillus subtilis was investigated. Evidence is presented that both of these activities determine the half-life of ΔermC mRNA. ...[more]

PMID: 21908660

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