Ontology highlight
ABSTRACT:
SUBMITTER: Farrow KN
PROVIDER: S-EPMC3209584 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Farrow Kathryn N KN Steinhorn Robin H RH
Handbook of experimental pharmacology 20110101 204
Pulmonary hypertension in the neonate is associated with multiple underlying problems such as respiratory distress syndrome, meconium aspiration syndrome, congenital diaphragmatic hernia, bronchopulmonary dysplasia, sepsis, or congenital heart disease. Because of the heterogeneous group of disorders, the therapeutic approach and response often depends on the underlying disease. In many of these conditions, there is evidence that cyclic nucleotide signaling and specifically phosphodiesterases (PD ...[more]