Ontology highlight
ABSTRACT:
SUBMITTER: Sampietro ML
PROVIDER: S-EPMC3209827 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Sampietro M Lourdes ML Trompet Stella S Verschuren Jeffrey J W JJ Talens Rudolf P RP Deelen Joris J Heijmans Bastiaan T BT de Winter Robbert J RJ Tio Rene A RA Doevendans Pieter A F M PA Ganesh Santhi K SK Nabel Elizabeth G EG Westra Harm-Jan HJ Franke Lude L van den Akker Erik B EB Westendorp Rudi G J RG Zwinderman Aeilko H AH Kastrati Adnan A Koch Werner W Slagboom P Eline PE de Knijff Peter P Jukema J Wouter JW
Human molecular genetics 20110830 23
Percutaneous coronary intervention (PCI) has become an effective therapy to treat obstructive coronary artery diseases (CAD). However, one of the major drawbacks of PCI is the occurrence of restenosis in 5-25% of all initially treated patients. Restenosis is defined as the re-narrowing of the lumen of the blood vessel, resulting in renewed symptoms and the need for repeated intervention. To identify genetic variants that are associated with restenosis, a genome-wide association study (GWAS) was ...[more]