Ontology highlight
ABSTRACT:
SUBMITTER: DeToma AS
PROVIDER: S-EPMC3210870 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Chemical Society reviews 20110804 2
This tutorial review presents descriptions of two amyloidogenic proteins, amyloid-β (Aβ) peptides and islet amyloid polypeptide (IAPP), whose misfolding propensities are implicated in Alzheimer's disease (AD) and type II diabetes, respectively. Protein misfolding diseases share similarities, as well as some unique protein-specific traits, that could contribute to the initiation and/or development of their associated conditions. Aβ and IAPP are representative amyloidoses and are used to highlight ...[more]