Ontology highlight
ABSTRACT:
SUBMITTER: Van Haastert PJ
PROVIDER: S-EPMC3212573 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
PloS one 20111109 11
Amoeboid cells crawl using pseudopods, which are convex extensions of the cell surface. In many laboratory experiments, cells move on a smooth substrate, but in the wild cells may experience obstacles of other cells or dead material, or may even move in liquid. To understand how cells cope with heterogeneous environments we have investigated the pseudopod life cycle of wild type and mutant cells moving on a substrate and when suspended in liquid. We show that the same pseudopod cycle can provide ...[more]