Ontology highlight
ABSTRACT:
SUBMITTER: Freire MA
PROVIDER: S-EPMC3212580 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Freire Marco Aurelio M MA Morya Edgard E Faber Jean J Santos Jose Ronaldo JR Guimaraes Joanilson S JS Lemos Nelson A M NA Sameshima Koichi K Pereira Antonio A Ribeiro Sidarta S Nicolelis Miguel A L MA
PloS one 20111109 11
Multielectrodes have been used with great success to simultaneously record the activity of neuronal populations in awake, behaving animals. In particular, there is great promise in the use of this technique to allow the control of neuroprosthetic devices by human patients. However, it is crucial to fully characterize the tissue response to the chronic implants in animal models ahead of the initiation of human clinical trials. Here we evaluated the effects of unilateral multielectrode implants on ...[more]