Ontology highlight
ABSTRACT:
SUBMITTER: Wegmann D
PROVIDER: S-EPMC321441 | biostudies-literature | 2004 Feb
REPOSITORIES: biostudies-literature
Wegmann Dominik D Hess Pablo P Baier Carola C Wieland Felix T FT Reinhard Constanze C
Molecular and cellular biology 20040201 3
In early secretory transport, coat recruitment for the formation of coat protein I (COPI) vesicles involves binding to donor Golgi membranes of the small GTPase ADP-ribosylation factor 1 and subsequent attachment of the cytoplasmic heptameric complex coatomer. Various hypotheses exist as to the precise role of and possible routes taken by COPI vesicles in the mammalian cell. Here we report the ubiquitous expression of two novel isotypes of coatomer subunits gamma- and zeta-COP that are incorpora ...[more]