Ontology highlight
ABSTRACT:
SUBMITTER: Trouillard M
PROVIDER: S-EPMC3215061 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
Trouillard Martin M Meunier Brigitte B Rappaport Fabrice F
Proceedings of the National Academy of Sciences of the United States of America 20111019 45
Mitochondria are the powerhouses of eukaryotic cells as they feed metabolism with its major substrate. Oxidative-phosphorylation relies on the generation, by an electron/proton transfer chain, of an electrochemical transmembrane potential utilized to synthesize ATP. Although these fundamental principles are not a matter of debate, the emerging picture of the respiratory chain diverges from the linear and fluid scheme. Indeed, a growing number of pieces of evidence point to membrane compartments ...[more]