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Intact mutS in laboratory-derived and clinical glycopeptide-intermediate Staphylococcus aureus strains.


ABSTRACT: The mutS gene of the methyl-directed mismatch repair system was sequenced in 10 parent and glycopeptide-intermediate Staphylococcus aureus strains. The mutS gene was intact in all strains studied. Hence, mutations in this gene had played no role in the development of vancomycin resistance in these strains.

SUBMITTER: Muthaiyan A 

PROVIDER: S-EPMC321528 | biostudies-literature | 2004 Feb

REPOSITORIES: biostudies-literature

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Intact mutS in laboratory-derived and clinical glycopeptide-intermediate Staphylococcus aureus strains.

Muthaiyan Arunachalam A   Jayaswal Radheshyam K RK   Wilkinson Brian J BJ  

Antimicrobial agents and chemotherapy 20040201 2


The mutS gene of the methyl-directed mismatch repair system was sequenced in 10 parent and glycopeptide-intermediate Staphylococcus aureus strains. The mutS gene was intact in all strains studied. Hence, mutations in this gene had played no role in the development of vancomycin resistance in these strains. ...[more]

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