Ontology highlight
ABSTRACT:
SUBMITTER: Mashalidis EH
PROVIDER: S-EPMC3215729 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Mashalidis Ellene H EH Mukherjee Tathagata T Sledź Paweł P Matak-Vinković Dijana D Boshoff Helena H Abell Chris C Barry Clifton E CE
PloS one 20111114 11
Despite intensive effort, the majority of the annotated Mycobacterium tuberculosis genome consists of genes encoding proteins of unknown or poorly understood function. For example, there are seven conserved hypothetical proteins annotated as homologs of pyridoxine 5'-phosphate oxidase (PNPOx), an enzyme that oxidizes pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) to form pyridoxal 5'-phosphate (PLP). We have characterized the function of Rv2607 from Mycobacterium tuberculosis H ...[more]