Human neutrophil peptide in lung chronic allograft dysfunction.
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ABSTRACT:
SUBMITTER: Reilly C
PROVIDER: S-EPMC3222782 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Publications
Human neutrophil peptide in lung chronic allograft dysfunction.
Reilly Cavan C Cervenka Tereza T Hertz Marshall I MI Becker Trisha T Wendt Chris H CH
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20111011 8
<h4>Context</h4>Our previous case-control study identified human neutrophil peptide (HNP) as a potential biomarker for bronchiolitis obliterans syndrome (BOS) in lung transplant recipients.<h4>Objective</h4>To prospectively validate HNP as a biomarker for BOS.<h4>Materials and methods</h4>HNP was measured by ELISA in bronchoalveolar lavage (BAL) fluid in lung transplant recipients.<h4>Results</h4>The first HNP measurement after reaching baseline pulmonary function was predictive of developing BO ...[more]
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