Epigenetic virtues of chromodomains.
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ABSTRACT:
SUBMITTER: Blus BJ
PROVIDER: S-EPMC3223283 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Publications
Epigenetic virtues of chromodomains.
Blus Bartlomiej J BJ Wiggins Kimberly K Khorasanizadeh Sepideh S
Critical reviews in biochemistry and molecular biology 20111025 6
The chromatin organization modifier domain (chromodomain) was first identified as a motif associated with chromatin silencing in Drosophila. There is growing evidence that chromodomains are evolutionary conserved across different eukaryotic species to control diverse aspects of epigenetic regulation. Although originally reported as histone H3 methyllysine readers, the chromodomain functions have now expanded to recognition of other histone and non-histone partners as well as interaction with nuc ...[more]
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