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Short report: Molecular insights for Giardia, Cryptosporidium, and soil-transmitted helminths from a facility-based surveillance system in Guatemala.


ABSTRACT: We molecularly characterized samples with Giardia, Cryptosporidium, and soil-transmitted helminths from a facility-based surveillance system for diarrhea in Santa Rosa, Guatemala. The DNA sequence analysis determined the presence of Giardia assemblages A (N = 7) and B (N = 12) and, Cryptosporidium hominis (N = 2) and Cryptosporidium parvum (N = 2), suggestive of different transmission cycles. All 41 samples with soil-transmitted helminths did not have the ?-tubulin mutation described for benzimidazole resistance, suggesting potential usefulness in mass drug administration campaigns.

SUBMITTER: Velasquez DE 

PROVIDER: S-EPMC3225167 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature

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Short report: Molecular insights for Giardia, Cryptosporidium, and soil-transmitted helminths from a facility-based surveillance system in Guatemala.

Velasquez Daniel E DE   Arvelo Wences W   Cama Vitaliano A VA   López Beatriz B   Reyes Lissette L   Roellig Dawn M DM   Kahn Geoffrey D GD   Lindblade Kimberly A KA  

The American journal of tropical medicine and hygiene 20111201 6


We molecularly characterized samples with Giardia, Cryptosporidium, and soil-transmitted helminths from a facility-based surveillance system for diarrhea in Santa Rosa, Guatemala. The DNA sequence analysis determined the presence of Giardia assemblages A (N = 7) and B (N = 12) and, Cryptosporidium hominis (N = 2) and Cryptosporidium parvum (N = 2), suggestive of different transmission cycles. All 41 samples with soil-transmitted helminths did not have the β-tubulin mutation described for benzimi  ...[more]

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