Comparing gene annotation enrichment tools for functional modeling of agricultural microarray data.

ABSTRACT:

Unlabelled

The widespread availability of microarray technology has driven functional genomics to the forefront as scientists seek to draw meaningful biological conclusions from their microarray results. Gene annotation enrichment analysis is a functional analysis technique that has gained widespread attention and for which many tools have been developed. Unfortunately, most of these tools have limited support for agricultural species. Here, we evaluate and compare four publicly available computational tools (Onto-Express, EasyGO, GOstat, and DAVID) that support analysis of gene expression datasets in agricultural species. We use AgBase as the functional annotation reference for agricultural species. The selected tools were evaluated based on i) available features, usage and access

SUBMITTER: van den Berg BH 

PROVIDER: S-EPMC3226198 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature