Ontology highlight
ABSTRACT:
SUBMITTER: You L
PROVIDER: S-EPMC3226768 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
You Lei L Berman Jeffrey S JS Anslyn Eric V EV
Nature chemistry 20111113 12
Reversible covalent bonding is often used for the creation of novel supramolecular structures, multi-component assemblies and sensing ensembles. Despite the remarkable success of dynamic covalent systems, the reversible binding of a mono-alcohol with high strength is challenging. Here, we show that a strategy of carbonyl activation and hemiaminal ether stabilization can be embodied in a four-component reversible assembly that creates a tetradentate ligand and incorporates secondary alcohols with ...[more]