Ontology highlight
ABSTRACT:
SUBMITTER: White JB
PROVIDER: S-EPMC3226999 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
White J Brandon JB Beckford Jeremy J Yadegarynia Sina S Ngo Nhi N Lialiutska Tetiana T d'Alarcao Marc M
Food chemistry 20120401 4
A common feature of both apoptosis and inflammation is the activation of caspases. Caspases are aspartate-directed cysteine proteases that have numerous cellular targets. It has been discovered that several flavonoids are inhibitors of caspases. Flavonoids are members of a family of polyphenolic compounds from plants that have many biological properties, one of which is the ability to induce cell death. Some flavonoids are selective inhibitors of particular caspases. Since some of the inhibitory ...[more]