Ontology highlight
ABSTRACT:
SUBMITTER: Shiu SY
PROVIDER: S-EPMC3227148 | biostudies-literature | 2008 Jul
REPOSITORIES: biostudies-literature
Shiu Shang-Ying SY Gatsonis Constantine C
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 20080701 1874
Binary test outcomes typically result from dichotomizing a continuous test variable, observable or latent. The effect of the threshold for test positivity on test sensitivity and specificity has been studied extensively in receiver operating characteristic (ROC) analysis. However, considerably less attention has been given to the study of the effect of the positivity threshold on the predictive value of a test. In this paper we present methods for the joint study of the positive (PPV) and negati ...[more]