Ontology highlight
ABSTRACT:
SUBMITTER: Li XB
PROVIDER: S-EPMC3227604 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Li Xiao-Bo XB Wang Shu-Qing SQ Xu Wei-Ren WR Wang Run-Ling RL Chou Kuo-Chen KC
PloS one 20111130 11
The worldwide spread of H1N1 avian influenza and the increasing reports about its resistance to the current drugs have made a high priority for developing new anti-influenza drugs. Owing to its unique function in assisting viruses to bind the cellular surface, a key step for them to subsequently penetrate into the infected cell, hemagglutinin (HA) has become one of the main targets for drug design against influenza virus. To develop potent HA inhibitors, the ZINC fragment database was searched f ...[more]