Ontology highlight
ABSTRACT:
SUBMITTER: Kollmannsberger C
PROVIDER: S-EPMC3228204 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Kollmannsberger Christian C Bjarnason Georg G Burnett Patrick P Creel Patricia P Davis Mellar M Dawson Nancy N Feldman Darren D George Suzanne S Hershman Jerome J Lechner Thomas T Potter Amy A Raymond Eric E Treister Nathaniel N Wood Laura L Wu Shenhong S Bukowski Ronald R
The oncologist 20110413 5
The multitargeted tyrosine-kinase inhibitor sunitinib has emerged as one of the standards of care for good- and intermediate-risk metastatic renal cell carcinoma. Although generally associated with acceptable toxicity, sunitinib exhibits a novel and distinct toxicity profile that requires monitoring and management. Fatigue, diarrhea, anorexia, oral changes, hand-foot syndrome and other skin toxicity, thyroid dysfunction, myelotoxicity, and hypertension seem to be the most common and clinically r ...[more]