Population screening for barrett esophagus: a prospective randomized pilot study.

ABSTRACT:

Objective

To assess the feasibility of unsedated transnasal endoscopy (uTNE) and video capsule endoscopy (VCE) as alternatives to sedated endoscopy (sEGD) as screening tools for Barrett esophagus (BE) and to obtain preliminary estimates of participation rates for sEGD, uTNE, and VCE when used for community BE screening in a population cohort.

Patients and methods

From February 1, 2009, to May 31, 2010, patients from Olmsted County, Minnesota, who were older than 50 years and had no history of known BE were randomized (stratified by age, sex, reflux symptoms noted in a validated questionnaire) into 3 groups for esophageal evaluation with sEGD, uTNE, or VCE. Participation rates and safety profiles were estimated.

Results

We contacted 127 patients to recruit 20 for each

SUBMITTER: Chang JY 

PROVIDER: S-EPMC3228617 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature