Angiogenic growth factor responses to long-term treadmill exercise in mice.
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ABSTRACT:
SUBMITTER: Pryor JS
PROVIDER: S-EPMC3229281 | biostudies-literature | 2010 Oct-Dec
REPOSITORIES: biostudies-literature
Publications
Angiogenic growth factor responses to long-term treadmill exercise in mice.
Pryor Janelle S JS Montani Jean-Pierre JP Adair Thomas H TH
Indian journal of physiology and pharmacology 20101001 4
We sought to determine whether VEGF and other angiogenic growth factors and their receptors might be subject to negative feedback regulation during two weeks of treadmill-exercise conditioning in inbred strains of mice. C57BL/6 mice exhibited greater VEGF mRNA and protein responses in gastrocnemius muscle to a single bout of treadmill exercise compared to BALB/c mice. The patterns of VEGF, VEGFR1, VEGFR2, Ang2 and Tie2 mRNA expression in gastrocnemius muscles of C57BL/6 mice during long-term exe ...[more]
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