Ontology highlight
ABSTRACT:
SUBMITTER: Tucker KR
PROVIDER: S-EPMC3229305 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Tucker Kevin R KR Lanni Eric J EJ Serebryannyy Leonid A LA Rubakhin Stanislav S SS Sweedler Jonathan V JV
Analytical chemistry 20111104 23
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) combines information-rich chemical detection with spatial localization of analytes. For a given instrumental platform and analyte class, the data acquired can represent a compromise between analyte extraction and spatial information. Here, we introduce an improvement to the spatial resolution achievable with MALDI MSI conducted with standard mass spectrometric systems that also reduces analyte migration during ma ...[more]