Ontology highlight
ABSTRACT:
SUBMITTER: Sato Y
PROVIDER: S-EPMC3230579 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
PloS one 20111205 12
M6a is a four-transmembrane protein that is abundantly expressed in the nervous system. Previous studies have shown that over-expression of this protein induces various cellular protrusions, such as neurites, filopodia, and dendritic spines. In this detailed characterization of M6a-induced structures, we found their varied and peculiar characteristics. Notably, the M6a-induced protrusions were mostly devoid of actin filaments or microtubules and exhibited free random vibrating motion. Moreover, ...[more]