Ontology highlight
ABSTRACT:
SUBMITTER: Schurch AC
PROVIDER: S-EPMC3230589 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Schürch Anita C AC Kremer Kristin K Hendriks Amber C A AC Freyee Benthe B McEvoy Christopher R E CR van Crevel Reinout R Boeree Martin J MJ van Helden Paul P Warren Robin M RM Siezen Roland J RJ van Soolingen Dick D
PloS one 20111205 12
The Beijing strain is one of the most successful genotypes of Mycobacterium tuberculosis worldwide and appears to be highly homogenous according to existing genotyping methods. To type Beijing strains reliably we developed a robust typing scheme using single nucleotide polymorphisms (SNPs) and regions of difference (RDs) derived from whole-genome sequencing data of eight Beijing strains. SNP/RD typing of 259 M. tuberculosis isolates originating from 45 countries worldwide discriminated 27 clonal ...[more]