MRI analysis in temporal lobe epilepsy: cortical thinning and white matter disruptions are related to side of seizure onset.
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ABSTRACT:
SUBMITTER: Kemmotsu N
PROVIDER: S-EPMC3230670 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Publications
MRI analysis in temporal lobe epilepsy: cortical thinning and white matter disruptions are related to side of seizure onset.
Kemmotsu Nobuko N Girard Holly M HM Bernhardt Boris C BC Bonilha Leonardo L Lin Jack J JJ Tecoma Evelyn S ES Iragui Vicente J VJ Hagler Donald J DJ Halgren Eric E McDonald Carrie R CR
Epilepsia 20111005 12
<h4>Purpose</h4>Past studies reported more widespread structural brain abnormalities in patients with left compared to right temporal lobe epilepsy (TLE), but the profile of these differences remains unknown. This study investigated the relationship between cortical thinning, white matter compromise, epilepsy variables, and the side of seizure onset, in patients with TLE.<h4>Methods</h4>We performed diffusion tensor imaging tractography and cortical thickness analyses of 18 patients with left TL ...[more]
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