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BioPAX support in CellDesigner.


ABSTRACT:

Motivation

BioPAX is a standard language for representing and exchanging models of biological processes at the molecular and cellular levels. It is widely used by different pathway databases and genomics data analysis software. Currently, the primary source of BioPAX data is direct exports from the curated pathway databases. It is still uncommon for wet-lab biologists to share and exchange pathway knowledge using BioPAX. Instead, pathways are usually represented as informal diagrams in the literature. In order to encourage formal representation of pathways, we describe a software package that allows users to create pathway diagrams using CellDesigner, a user-friendly graphical pathway-editing tool and save the pathway data in BioPAX Level 3 format.

Availability

The plug-in is freely available and can be downloaded at ftp://ftp.pantherdb.org/CellDesigner/plugins/BioPAX/ CONTACT: huaiyumi@usc.edu

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: Mi H 

PROVIDER: S-EPMC3232372 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature

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Publications

BioPAX support in CellDesigner.

Mi Huaiyu H   Muruganujan Anushya A   Demir Emek E   Matsuoka Yukiko Y   Funahashi Akira A   Kitano Hiroaki H   Thomas Paul D PD  

Bioinformatics (Oxford, England) 20111021 24


<h4>Motivation</h4>BioPAX is a standard language for representing and exchanging models of biological processes at the molecular and cellular levels. It is widely used by different pathway databases and genomics data analysis software. Currently, the primary source of BioPAX data is direct exports from the curated pathway databases. It is still uncommon for wet-lab biologists to share and exchange pathway knowledge using BioPAX. Instead, pathways are usually represented as informal diagrams in t  ...[more]

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