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Complete genome sequence of the neonatal-meningitis-associated Escherichia coli strain CE10.


ABSTRACT: Neonatal bacterial meningitis continues to be an important cause of mortality and morbidity worldwide. Escherichia coli possessing the K1 capsular polysaccharide is the most common Gram-negative pathogen causing neonatal meningitis. Here we present the complete genome sequence of neonatal meningitis-associated E. coli strain CE10, a unique K1 strain with a functional type III secretion system. Functional analysis of the genome should enhance our knowledge of the pathogenesis of neonatal E. coli K1 meningitis.

SUBMITTER: Lu S 

PROVIDER: S-EPMC3232859 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature

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Complete genome sequence of the neonatal-meningitis-associated Escherichia coli strain CE10.

Lu Shuting S   Zhang Xiaobing X   Zhu Yafang Y   Kim Kwang Sik KS   Yang Jian J   Jin Qi Q  

Journal of bacteriology 20111201 24


Neonatal bacterial meningitis continues to be an important cause of mortality and morbidity worldwide. Escherichia coli possessing the K1 capsular polysaccharide is the most common Gram-negative pathogen causing neonatal meningitis. Here we present the complete genome sequence of neonatal meningitis-associated E. coli strain CE10, a unique K1 strain with a functional type III secretion system. Functional analysis of the genome should enhance our knowledge of the pathogenesis of neonatal E. coli  ...[more]

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