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A chemical reporter strategy to probe glycoprotein fucosylation.

ABSTRACT: Fucosylated glycoproteins are involved in many cell-cell recognition events and are markers of embryonic and malignant tissue. Here we report a method for rapid profiling of fucosylated glycoproteins from human cells using 6-azido fucose as a metabolic label.

SUBMITTER: Rabuka D

PROVIDER: S-EPMC3233198 | biostudies-literature | 2006 Sep

REPOSITORIES: biostudies-literature

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A chemical reporter strategy to probe glycoprotein fucosylation.

Rabuka David D Hubbard Sarah C SC Laughlin Scott T ST Argade Sulabha P SP Bertozzi Carolyn R CR

Journal of the American Chemical Society 20060901 37

Fucosylated glycoproteins are involved in many cell-cell recognition events and are markers of embryonic and malignant tissue. Here we report a method for rapid profiling of fucosylated glycoproteins from human cells using 6-azido fucose as a metabolic label. ...[more]

PMID: 16967952

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