Ontology highlight
ABSTRACT:
SUBMITTER: Luo R
PROVIDER: S-EPMC3233205 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
The annals of applied statistics 20110101 2A
Recent technological advances have made it possible to simultaneously measure multiple protein activities at the single cell level. With such data collected under different stimulatory or inhibitory conditions, it is possible to infer the causal relationships among proteins from single cell interventional data. In this article we propose a Bayesian hierarchical modeling framework to infer the signaling pathway based on the posterior distributions of parameters in the model. Under this framework, ...[more]