Ontology highlight
ABSTRACT:
SUBMITTER: Cheung ID
PROVIDER: S-EPMC3235368 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Cheung Isla D ID Bagnat Michel M Ma Taylur P TP Datta Anirban A Evason Kimberley K Moore John C JC Lawson Nathan D ND Mostov Keith E KE Moens Cecilia B CB Stainier Didier Y R DY
Developmental biology 20111012 1
The intrahepatic biliary ducts transport bile produced by the hepatocytes out of the liver. Defects in biliary cell differentiation and biliary duct remodeling cause a variety of congenital diseases including Alagille Syndrome and polycystic liver disease. While the molecular pathways regulating biliary cell differentiation have received increasing attention (Lemaigre, 2010), less is known about the cellular behavior underlying biliary duct remodeling. Here, we have identified a novel gene, clau ...[more]