Ontology highlight
ABSTRACT:
SUBMITTER: Molinari C
PROVIDER: S-EPMC3236016 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Molinari Chiara C Ballardini Michela M Teodorani Nazario N Giannini Massimo M Zoli Wainer W Emiliani Ermanno E Lucci Enrico E Passardi Alessandro A Rosetti Paola P Saragoni Luca L Guidoboni Massimo M Amadori Dino D Calistri Daniele D
Radiation oncology (London, England) 20111118
<h4>Background</h4>Neoadjuvant chemoradiotherapy is the treatment of choice in advanced rectal cancer, even though there are many patients who will not benefit from it. There are still no effective methods for predicting which patients will respond or not. The present study aimed to define the genomic profile of rectal tumors and to identify alterations that are predictive of response in order to optimize therapeutic strategies.<h4>Methods</h4>Forty-eight candidates for neoadjuvant chemoradiothe ...[more]