Ontology highlight
ABSTRACT:
SUBMITTER: Liu H
PROVIDER: S-EPMC3236125 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Liu Hongtao H Rich Elizabeth S ES Godley Lucy L Odenike Olatoyosi O Joseph Loren L Marino Susana S Kline Justin J Nguyen Vu V Cunningham John J Larson Richard A RA del Cerro Paula P Schroeder Linda L Pape Lisa L Stock Wendy W Wickrema Amittha A Artz Andrew S AS van Besien Koen K
Blood 20111005 24
We conducted a 45 patient prospective study of reduced-intensity conditioning (RIC) and transplantation of unrelated umbilical cord blood (UCB) and CD34(+) stem cells from a haploidentical family member. Median age was 50 years; weight was 80 kg. Fifty-eight percent had active disease. Neutrophil engraftment occurred at 11 days (interquartile range [IQR], 9-15) and platelet engraftment at 19 days (IQR, 15-33). In the majority of patients, early haploidentical engraftment was replaced by durable ...[more]