Ontology highlight
ABSTRACT:
SUBMITTER: Philipp U
PROVIDER: S-EPMC3236222 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
PloS one 20111212 12
A dominantly inherited syndrome associated with hypopigmentation, heterochromia irides, colobomatous eyes and bilateral hearing loss has been ascertained in Fleckvieh cattle (German White Fleckvieh syndrome). This syndrome has been mapped to bovine chromosome (BTA) 22 using a genome-wide association study with the bovine high density single nucleotide polymorphism array. An R210I missense mutation has been identified within microphthalmia-associated transcription factor (MITF) as responsible for ...[more]