DNA binding and unwinding by self-assembled supramolecular hetero-bimetallacycles.

ABSTRACT: Two new tetracationic hetero-bimetallacycles were prepared from a bis-pyridine amide ligand and metal (Pd and Pt) acceptors. We found that both self-assembled hetero-bimetallacycles bind and unwind supercoiled DNA as established by photophysical and gel electrophoresis analyses, respectively.

SUBMITTER: Mishra A 

PROVIDER: S-EPMC3237687 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature