Dataset Information

Protein status elicits compensatory changes in food intake and food preferences.

ABSTRACT:

Background

Protein is an indispensable component within the human diet. It is unclear, however, whether behavioral strategies exist to avoid shortages.

Objective

The objective was to investigate the effect of a low protein status compared with a high protein status on food intake and food preferences.

Design

We used a randomized crossover design that consisted of a 14-d fully controlled dietary intervention involving 37 subjects [mean ± SD age: 21 ± 2 y; BMI (in kg/m(2)): 21.9 ± 1.5] who consumed individualized, isoenergetic diets that were either low in protein [0.5 g protein · kg body weight (BW)(-1) · d(-1)] or high in protein (2.0 g protein · kg BW(-1) · d(-1)). The diets were followed by an ad libitum phase of 2.5 d, during which a large array of food items was available, and protein and energy intakes were measured.

Results

We showed that in the ad libitum phase protein intake was 13% higher after the low-protein diet than after the high-protein diet (253 ± 70 compared with 225 ± 63 g, P < 0.001), whereas total energy intake was not different. The higher intake of protein was evident throughout the ad libitum phase of 2.5 d. In addition, after the low-protein diet, food preferences for savory high-protein foods were enhanced.

Conclusions

After a protein deficit, food intake and food preferences show adaptive changes that suggest that compensatory mechanisms are induced to restore adequate protein status. This indicates that there are human behavioral strategies present to avoid protein shortage and that these involve selection of savory high-protein foods. This trial was registered with the Dutch Trial register at http://www.trialregister.nl as NTR2491.

SUBMITTER: Griffioen-Roose S

PROVIDER: S-EPMC3238463 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Protein status elicits compensatory changes in food intake and food preferences.

Griffioen-Roose Sanne S Mars Monica M Siebelink Els E Finlayson Graham G Tomé Daniel D de Graaf Cees C

The American journal of clinical nutrition 20111207 1

<h4>Background</h4>Protein is an indispensable component within the human diet. It is unclear, however, whether behavioral strategies exist to avoid shortages.<h4>Objective</h4>The objective was to investigate the effect of a low protein status compared with a high protein status on food intake and food preferences.<h4>Design</h4>We used a randomized crossover design that consisted of a 14-d fully controlled dietary intervention involving 37 subjects [mean ± SD age: 21 ± 2 y; BMI (in kg/m(2)): 2 ...[more]

PMID: 22158729

Similar Datasets

Project description:Karl, J. Philip, Renee E. Cole, Claire E. Berryman, Graham Finlayson, Patrick N. Radcliffe, Matthew T. Kominsky, Nancy E. Murphy, John W. Carbone, Jennifer C. Rood, Andrew J. Young, and Stefan M. Pasiakos. Appetite suppression and altered food preferences coincide with changes in appetite-mediating hormones during energy deficit at high altitude, but are not affected by protein intake. High Alt Med Biol. 19:156-169, 2018.-Anorexia and unintentional body weight loss are common during high altitude (HA) sojourn, but underlying mechanisms are not fully characterized, and the impact of dietary macronutrient composition on appetite regulation at HA is unknown. This study aimed to determine the effects of a hypocaloric higher protein diet on perceived appetite and food preferences during HA sojourn and to examine longitudinal changes in perceived appetite, appetite mediating hormones, and food preferences during acclimatization and weight loss at HA. Following a 21-day level (SL) period, 17 unacclimatized males ascended to and resided at HA (4300?m) for 22 days. At HA, participants were randomized to consume measured standard-protein (1.0?g protein/kg/d) or higher protein (2.0?g/kg/d) hypocaloric diets (45% carbohydrate, 30% energy restriction) and engaged in prescribed physical activity to induce an estimated 40% energy deficit. Appetite, food preferences, and appetite-mediating hormones were measured at SL and at the beginning and end of HA. Diet composition had no effect on any outcome. Relative to SL, appetite was lower during acute HA (days 0 and 1), but not different after acclimatization and weight loss (HA day 18), and food preferences indicated an increased preference for sweet- and low-protein foods during acute HA, but for high-fat foods after acclimatization and weight loss. Insulin, leptin, and cholecystokinin concentrations were elevated during acute HA, but not after acclimatization and weight loss, whereas acylated ghrelin concentrations were suppressed throughout HA. Findings suggest that appetite suppression and altered food preferences coincide with changes in appetite-mediating hormones during energy deficit at HA. Although dietary protein intake did not impact appetite, the possible incongruence with food preferences at HA warrants consideration when developing nutritional strategies for HA sojourn.

Dataset Information

Protein status elicits compensatory changes in food intake and food preferences.

Background

Objective

Design

Results

Conclusions

Publications

Protein status elicits compensatory changes in food intake and food preferences.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure