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4-[(2-Hy-droxy-naphthalen-1-yl)(morpholin-4-yl)meth-yl]benzonitrile.

ABSTRACT: The title compound, C(22)H(20)N(2)O(2), was synthesized via a multicomponent reaction using naphthalen-2-ol, morpholine and 4-formyl-benzonitrile. The dihedral angle between the naphthalene ring system and the benzene ring is 81.25?(10)°. The morpholine ring adopts a chair conformation. The mol-ecular conformation is stabilized by intra-molecular O-H?N and C-H?O hydrogen bonds. In the crystal, inter-molecular C-H?N hydrogen bonds link mol-ecules into helical chains running parallel to the c axis.

SUBMITTER: Chen XY

PROVIDER: S-EPMC3239108 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature

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4-[(2-Hy-droxy-naphthalen-1-yl)(morpholin-4-yl)meth-yl]benzonitrile.

Chen Xin-Yuan XY Zhao Min-Min MM Qian Xu X Hou Shao-Gang SG

Acta crystallographica. Section E, Structure reports online 20111130 Pt 12

The title compound, C(22)H(20)N(2)O(2), was synthesized via a multicomponent reaction using naphthalen-2-ol, morpholine and 4-formyl-benzonitrile. The dihedral angle between the naphthalene ring system and the benzene ring is 81.25 (10)°. The morpholine ring adopts a chair conformation. The mol-ecular conformation is stabilized by intra-molecular O-H⋯N and C-H⋯O hydrogen bonds. In the crystal, inter-molecular C-H⋯N hydrogen bonds link mol-ecules into helical chains running parallel to the c axis ...[more]

PMID: 22199956

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