Ontology highlight
ABSTRACT:
SUBMITTER: Sen P
PROVIDER: S-EPMC3241646 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
Sen Payel P Ghosh Sujana S Pugh B Franklin BF Bartholomew Blaine B
Nucleic acids research 20110810 21
SWI/SNF is an ATP-dependent remodeler that mobilizes nucleosomes and has important roles in gene regulation. The catalytic subunit of SWI/SNF has an ATP-dependent DNA translocase domain that is essential for remodeling. Besides the DNA translocase domain there are other domains in the catalytic subunit of SWI/SNF that have important roles in mobilizing nucleosomes. One of these domains, termed SnAC (Snf2 ATP Coupling), is conserved in all eukaryotic SWI/SNF complexes and is located between the A ...[more]