Ontology highlight
ABSTRACT:
SUBMITTER: Song GJ
PROVIDER: S-EPMC3241829 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Song Gyun Jee GJ Barrick Stacey S Leslie Kristen L KL Bauer Philip M PM Alonso Veronica V Friedman Peter A PA Fiaschi-Taesch Nathalie M NM Bisello Alessandro A
Arteriosclerosis, thrombosis, and vascular biology 20111027 1
<h4>Objective</h4>The Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) is a scaffolding protein known to regulate ion homeostasis in the kidney and intestine. Previous work showed that EBP50 expression increases after balloon injury in rat carotids. This study was designed to determine the role of EBP50 on vascular smooth muscle cells (VSMC) proliferation and the development of neointimal hyperplasia.<h4>Methods and results</h4>Wire injury was performed in wild type (WT) and EBP50 knockout ...[more]