Ontology highlight
ABSTRACT:
SUBMITTER: Lichterfeld M
PROVIDER: S-EPMC3241906 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Lichterfeld Mathias M Gandhi Rajesh T RT Simmons Rachel P RP Flynn Theresa T Sbrolla Amy A Yu Xu G XG Basgoz Nesli N Mui Stanley S Williams Katie K Streeck Hendrik H Burgett-Yandow Nicole N Roy Gilbert G Janssens Michel M Pedneault Louise L Vandepapelière Pierre P Koutsoukos Marguerite M Demoitié Marie-Ange MA Bourguignon Patricia P McNally Lisa L Voss Gerald G Altfeld Marcus M
Journal of acquired immune deficiency syndromes (1999) 20120101 1
<h4>Background</h4>Induction of HIV-1-specific CD4(+) T-cell responses by therapeutic vaccination represents an attractive intervention to potentially increase immune control of HIV-1.<h4>Methods</h4>We performed a double-blinded, randomized, placebo-controlled clinical trial to determine the safety and immunogenicity of GlaxoSmithKline Biologicals' HIV-1 gp120/NefTat subunit protein vaccine formulated with the AS02(A) Adjuvant System in subjects with well-controlled chronic HIV-1 infection on h ...[more]