Early developments in gene-expression profiling of breast tumors: potential for increasing black-white patient disparities in breast cancer outcomes?
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ABSTRACT:
SUBMITTER: Odierna DH
PROVIDER: S-EPMC3242007 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
Publications
Early developments in gene-expression profiling of breast tumors: potential for increasing black-white patient disparities in breast cancer outcomes?
Odierna Donna H DH Afable-Munsuz Aimee A Ikediobi Ogechi O Beattie Mary M Knight Sara S Ko Michelle M Wilson Adrienne A Ponce Ninez A NA
Personalized medicine 20111101 6
New prognostic tests, such as gene-expression profiling (GEP) of breast tumors, are expected to prolong survival and improve the quality of life for many breast cancer patients. In this article, we argue that GEP has not been adequately validated in minority populations, and that both biological and social factors might affect the broad utility of these tests in diverse populations. We suggest that the widespread use of this technology could potentially lead to suboptimal treatment for black wom ...[more]
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