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Helicobacter pylori persistence: biology and disease.


ABSTRACT: Helicobacter pylori are bacteria that have coevolved with humans to be transmitted from person to person and to persistently colonize the stomach. Their population structure is a model for the ecology of the indigenous microbiota. A well-choreographed equilibrium between bacterial effectors and host responses permits microbial persistence and health of the host but confers risk of serious diseases, including peptic ulceration and gastric neoplasia.

SUBMITTER: Blaser MJ 

PROVIDER: S-EPMC324548 | biostudies-literature | 2004 Feb

REPOSITORIES: biostudies-literature

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Helicobacter pylori persistence: biology and disease.

Blaser Martin J MJ   Atherton John C JC  

The Journal of clinical investigation 20040201 3


Helicobacter pylori are bacteria that have coevolved with humans to be transmitted from person to person and to persistently colonize the stomach. Their population structure is a model for the ecology of the indigenous microbiota. A well-choreographed equilibrium between bacterial effectors and host responses permits microbial persistence and health of the host but confers risk of serious diseases, including peptic ulceration and gastric neoplasia. ...[more]

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