Ontology highlight
ABSTRACT:
SUBMITTER: Bari R
PROVIDER: S-EPMC3245733 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Bari Rafijul R Guo Qiusha Q Xia Bing B Zhang Yanhui H YH Giesert Eldon E EE Levy Shoshana S Zheng Jie J JJ Zhang Xin A XA
Biochemical and biophysical research communications 20111102 4
Tetraspanins have gained increased attention due to their functional versatility. But the universal cellular mechanism that governs such versatility remains unknown. Herein we present the evidence that tetraspanins CD81 and CD82 regulate the formation and/or development of cell membrane protrusions. We analyzed the ultrastructure of the cells in which a tetraspanin is either overexpressed or ablated using transmission electron microscopy. The numbers of microvilli on the cell surface were counte ...[more]