Ontology highlight
ABSTRACT:
SUBMITTER: Lang S
PROVIDER: S-EPMC3245843 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Lang Silvia S Kirchberger Paul C PC Gruber Christian J CJ Redzej Adam A Raffl Sandra S Zellnig Guenther G Zangger Klaus K Zechner Ellen L EL
Molecular microbiology 20111108 5
Bacterial conjugation is a form of type IV secretion that transports protein and DNA to recipient cells. Specific bacteriophage exploit the conjugative pili and cell envelope spanning protein machinery of these systems to invade bacterial cells. Infection by phage R17 requires F-like pili and coupling protein TraD, which gates the cytoplasmic entrance of the secretion channel. Here we investigate the role of TraD in R17 nucleoprotein uptake and find parallels to secretion mechanisms. The relaxos ...[more]