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Synthesis of the reported structure of trans-africanan-1?-ol.

ABSTRACT: A trisubstituted cyclopentane chiron has been prepared by dynamic kinetic reduction of a pulegone-derived ?-keto ester. This chiron served as the starting material for the synthesis of the reported structure of the tricyclic sesquiterpene trans-africanan-1?-ol. The synthetic material was not congruent with the natural product.

SUBMITTER: Taber DF

PROVIDER: S-EPMC3248816 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature

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Synthesis of the reported structure of trans-africanan-1α-ol.

Taber Douglass F DF Bai Sha S Tian Weiwei W

The Journal of organic chemistry 20111110 23

A trisubstituted cyclopentane chiron has been prepared by dynamic kinetic reduction of a pulegone-derived β-keto ester. This chiron served as the starting material for the synthesis of the reported structure of the tricyclic sesquiterpene trans-africanan-1α-ol. The synthetic material was not congruent with the natural product. ...[more]

PMID: 22053815

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