Dataset Information
Computationally guided organometallic chemistry: preparation of the heptacyclic pyrazine core of ritterazine N.
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ABSTRACT:
SUBMITTER: Taber DF
PROVIDER: S-EPMC3248823 | biostudies-literature | 2006 Mar
REPOSITORIES: biostudies-literature
Publications
Computationally guided organometallic chemistry: preparation of the heptacyclic pyrazine core of ritterazine N.
The Journal of organic chemistry 20060301 7
Diels-Alder cycloaddition of 10 followed by Wittig homologation and intramolecular diene cyclozirconation of the resulting triene under equilibrating conditions led to the tricyclic 6-6-5 ketone 5 with high diastereocontrol. The derived alpha-azido ketone 16 cyclized efficiently to the heptacyclic pyrazine core of ritterazine N. ...[more]