Ontology highlight
ABSTRACT:
SUBMITTER: Sahota P
PROVIDER: S-EPMC3250280 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Sahota Preeti P Savitz Sean I SI
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20110701 3
Stroke is one of the leading causes of death and disability worldwide. Current treatment strategies for ischemic stroke primarily focus on reducing the size of ischemic damage and rescuing dying cells early after occurrence. To date, intravenous recombinant tissue plasminogen activator is the only United States Food and Drug Administration approved therapy for acute ischemic stroke, but its use is limited by a narrow therapeutic window. The pathophysiology of stroke is complex and it involves ex ...[more]